Computational Scientist (Medicinal Chemistry) Job at Axiom, San Francisco, CA

eXNublduZUt3T0t0WUJZWGdzcHdIcTN6VVE9PQ==
  • Axiom
  • San Francisco, CA

Job Description

Charter:

Be a founding member of a team setting out to build the first accurate AI systems for replacing lab and animal toxicity experiments with AI models

What are we looking for:

We only want to hire people who deeply inspire us and relentlessly push us to be better. They must level up the entire team, bringing significant energy and a sense of awe. They should have great taste for what matters, see what needs doing, and do it with great urgency. They should just act. There must be a deep curiosity for all facets of Axiom, a greater ambition fueling their excitement for what we do. They need to be cracked, technically excellent, obsessive masters of their craft. They're irrational; they could work in big tech, but they know it will not satisfy them: they want the challenge of solving a brutally difficult scientific problem and building a generational company from the ground up, as well as the rewards and glory that will come as a result.

What you will be doing:

  • Lead the development of AI models for predicting human clinical outputs by analyzing model outputs to pinpoint high-performing and underperforming use cases.
  • Collaborate with machine learning researchers to drive the development of cutting-edge models for predicting human clinical outcomes.
  • Direct model usage, interpretability, refinement, and improvement.
  • Clean, curate, and process large-scale chemistry datasets spanning many unique compounds for model evaluation, training, and more.
  • Partner directly with top drug hunters at Pfizer, Takeda, Gilead, Merck, and others to interpret model predictions and accelerate decision-making.
  • Design new strategies to expand our experimental and molecular dataset intelligently—driven by data, ML performance, and real-world drug hunter usage.
  • Influence active drug programs and play a role in evolving how the world’s leading pharma teams develop safe, effective medicines.
  • Help shape Axiom’s product based on customer feedback and insights you uncover from speaking and developing relationships with the world's leading drug hunters.

Expertise which sparks our interest:

  • Likely either has an advanced degree in chemistry, cheminformatics, or computational chemistry, or has industry experience at a drug discovery company.
  • Might identify as a ML for chemistry researcher, computational chemist, medicinal chemist, or cheminformatics scientist.
  • Experience working with drug hunters on advancing real drugs towards the clinic.
  • Deep understanding of the current limitations of preclinical models and a passion, vision to make them extremely better.
  • Presentation and soft skills with the ability to own customer relationships and partnerships with both biotech companies and big pharma.
  • Coding and statistics background: should be comfortable with python, with cheminformatics libraries like rdkit and datamol, scientific computing libraries like numpy, and ideally also with data processing (SQL, pandas, basic cloud computing).
  • Experience analyzing massive chemical datasets and diving conclusions based on data science and chemistry.
#J-18808-Ljbffr

Job Tags

Full time,

Similar Jobs

Peraton

Junior/Entry Level Software Engineer Job at Peraton

 ...opportunity to grow your skills through hands-on development and mentorship in a collaborative environment. Roles & Responsibilities: Develop, maintain, and enhance Java-based web applications Collaborate with a team of 1012 engineers in an Agile environment... 

ProPivotal Staffing

Senior Tax Professional (CPA required) Job at ProPivotal Staffing

 ...Senior Tax Professional (CPA required) A growing CPA firm islooking for a Senior Tax Professional. The firm offers a hybrid work...  ...model,with in-office days on Tuesday, Wednesday, and Thursday, and remote work onMonday and Friday. What to know: Base salary... 

Cousin's Air

HVAC - Field Supervisor for Service Department Job at Cousin's Air

 ...Cousins Air is a premier HVAC service provider in South Florida, specializing in the installation and service of air conditioning systems...  ...Maintain clear and effective communication with dispatch, management, and field technicians to support smooth operations. Oversee... 

KBR

Travel Coordinator, Intermediate Job at KBR

 ...position is contingent upon contract award Key Responsibilities: Perform all functions of personnel (government, civilian, military, and contractor) travel for official government business Notify in-country representatives of expected travel, attain country... 

Ashby

Design Engineer - Canada Job at Ashby

 ...improvement to a common component cascades throughout our app (short video below). Heres an impromptu quote from Arjun in our company Slack of what its like to build a feature at Ashby: And a demo of one of these building blocks: Give Engineers Ownership &...